Florida issues no single med-spa license. Three things do the job: every injector (RN, NP, PA, MD/DO) holds an individual Department of Health license; a supervising medical director must be a licensed physician (or, within their scope, an APRN/PA under protocol); and the business itself needs an AHCA Health Care Clinic license unless it qualifies for a Certificate of Exemption (for example, wholly owned by licensed practitioners).
Non-physician ownership is legal in Florida, which is why the AHCA clinic license or exemption matters: it is the state's record that the business has a designated medical director and has passed inspection or qualified for exemption.
Every listing here shows whether the business appears on AHCA's Health Care Clinic or Exemption register, and links to the state search. A spa that is on neither list and offers Botox, fillers or lasers deserves a direct question about who its medical director is.